Indications
Barberry is the root, stem bark or fruit of Berberis shrubs (such as Berberis aristata, known in Ayurveda as Daruharidra, and Berberis vulgaris). In Unani and Ayurvedic medicine it is traditionally used in preparations for piles (haemorrhoids), for digestive complaints and liver support, and for skin and eye problems. Its main active compound, berberine, has been studied for blood sugar and cholesterol, but evidence for barberry products themselves is limited, and they do not cure piles or diabetes.
How It Works
Berberine, the yellow alkaloid in barberry, has antimicrobial and anti inflammatory effects in laboratory studies, and in people it can lower blood sugar and blood fats. The bitter taste is thought to stimulate digestion and bile flow. In piles preparations it is used with other herbs to reduce swelling and bleeding.
Dosage and Administration
Take as directed on the label or by a registered practitioner. Do not take more than recommended, and do not use for long periods without advice.
Interactions
- Berberine can increase the levels of some medicines, including Ciclosporin, Tacrolimus and certain heart medicines, by slowing their breakdown in the liver.
- It may add to the effect of diabetes medicines such as Metformin, Gliclazide or Insulin, causing low blood sugar.
- It may add to the effect of blood pressure medicines and sedatives.
- Tell your doctor about all medicines you take.
Contraindications
- Pregnancy and breastfeeding.
- Newborns and infants.
- Allergy to barberry or any ingredient.
Side Effects
Possible effects include stomach upset, cramps, constipation or diarrhoea, nausea and wind. Rarely, low blood sugar or low blood pressure may occur.
Get urgent medical help if you have signs of a serious allergic reaction (swelling of the face or throat, difficulty breathing, widespread rash), heavy rectal bleeding, fainting, or yellowing of the skin or eyes.
Pregnancy and Lactation
Do not use during pregnancy or breastfeeding. Berberine can cross the placenta and pass into breast milk, and it may worsen jaundice in newborn babies.
Precautions and Warnings
- Rectal bleeding should always be checked by a doctor, because it can have serious causes other than piles.
- People with diabetes should monitor blood sugar.
- Not for children unless advised by a practitioner.
Overdose
Large amounts of barberry or berberine can cause vomiting, diarrhoea, nosebleeds, low blood pressure, breathing problems and drowsiness. Seek medical help straight away if a large amount has been taken.
Therapeutic Class
Unani and Ayurvedic herbal preparation (used in anti haemorrhoidal and digestive remedies).
Storage
Store below 30°C in a dry place, away from light and out of the reach of children.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.