Indications
Collagen Type-I is the main structural protein of skin, bone, tendons and ligaments. As a dietary supplement (usually from bovine, chicken or fish sources, either hydrolysed into small peptides or in an undenatured form) it is used to support joint comfort in osteoarthritis, tendon and ligament health, bone strength, and skin firmness and hydration. Evidence from studies is mixed to modest, and it is a supplement, not a treatment for disease.
How It Works
Hydrolysed collagen is broken down in the gut into amino acids and small peptides (such as those containing proline and hydroxyproline), which may act as building blocks and signals for cells that make new collagen in cartilage, tendons, bone and skin. Undenatured collagen is thought to work differently, by calming the immune reaction against joint cartilage through the gut.
Dosage and Administration
Take it as directed on the label, as the amount differs greatly between hydrolysed and undenatured forms. It can be taken with or without food. Benefits, if any, usually take several weeks to months of regular use.
Interactions
No important drug interactions are known. Some products also contain Vitamin C, Calcium or other ingredients, so check the label and tell your doctor about all supplements you take.
Contraindications
Do not use it if you are allergic to its source, for example fish, shellfish, egg or beef. People who avoid certain animal products for religious or dietary reasons should check the source on the label.
Side Effects
It is usually well tolerated. Some people notice mild stomach upset, a feeling of fullness, heartburn or an unpleasant taste. Allergic reactions can occur in people sensitive to the source.
Get urgent medical help if you have swelling of the face, lips or throat, difficulty breathing, or a widespread itchy rash after taking it.
Pregnancy and Lactation
Collagen is a food protein, but there is little research on supplements during pregnancy or breastfeeding. Ask your doctor before use.
Precautions and Warnings
Joint pain, swelling or injury should be assessed by a doctor. People with kidney disease who are told to limit protein should ask a doctor first. Choose products from reliable manufacturers.
Overdose
Taking more than recommended is unlikely to be dangerous but may cause stomach upset. Seek medical advice if symptoms are troublesome.
Therapeutic Class
Dietary supplement (structural protein for joints, bone and skin).
Storage
Store below 30°C in a dry place, away from light and out of the reach of children.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.