Indications
D-Pantothenol (Dexpanthenol) is the alcohol form of pantothenic acid (vitamin B5). It is found as an ingredient in multivitamin and amino acid injections and tonics, including some products made for animals (livestock and poultry), where it supports general nutrition, recovery and blood formation. In human medicine, injections have been used to help restart bowel movement after abdominal surgery, and creams and ointments are widely used to soothe and heal dry, cracked or irritated skin, nappy rash, minor burns and sore nipples.
How It Works
The body converts D-Pantothenol into pantothenic acid, which is needed to make coenzyme A, a substance involved in energy production and the building of fats, hormones and new cells. On the skin it attracts moisture and supports skin repair. In the gut it supports the chemical signals that drive normal bowel movement.
Dosage and Administration
Injections are given by a doctor, nurse or, for animal products, a veterinarian, as prescribed or as directed on the label. Veterinary products must be used only in the animals and at the doses stated on the label. Creams and ointments: apply a thin layer once or several times daily as directed on the label.
Interactions
Injections should not be given within 12 hours of Neostigmine or similar medicines that stimulate the bowel, and with care in people taking Succinylcholine (a muscle relaxant used in anaesthesia). No important interactions are known for creams.
Contraindications
Do not use if allergic to Dexpanthenol or any ingredient of the product. Injections are not used in people with haemophilia or a mechanical blockage of the bowel.
Side Effects
- Skin products: rarely itching, redness or rash
- Injections: occasional stomach cramps, diarrhoea, itching or low blood pressure
Get urgent medical help if you notice hives, swelling of the face or throat, difficulty breathing or fainting after an injection.
Pregnancy and Lactation
Skin products are considered safe in pregnancy and breastfeeding; if used on the nipples, wipe off before feeding unless the label says otherwise. Injections should be used during pregnancy or breastfeeding only if a doctor decides they are needed.
Precautions and Warnings
Veterinary injections are not for human use; follow the withdrawal period on the label before meat, milk or eggs from treated animals are used for food. Do not use skin products on deep or infected wounds without medical advice.
Overdose
D-Pantothenol has low toxicity. Large doses may cause diarrhoea. Seek medical or veterinary advice if a large amount has been given.
Therapeutic Class
Vitamin B5 (provitamin); skin protectant and healing agent; nutritional supplement.
Storage
Store below 30°C in a dry place, away from light and out of the reach of children. Injections: store as directed on the pack.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.