Indications
Dexpanthenol (also called Panthenol) is a form of vitamin B5 (pantothenic acid). By mouth or injection it is used as part of vitamin B complex products to prevent or treat B vitamin deficiency. Applied to the skin, it helps heal minor wounds, burns, sunburn, cracked nipples, nappy rash and dry or irritated skin. Injections are sometimes used in hospital to help restart bowel movement after abdominal surgery.
How It Works
In the body Dexpanthenol is turned into pantothenic acid, which is needed to make coenzyme A, a substance that cells use to release energy from food and to build fats and proteins. On the skin it draws in moisture, supports the skin barrier and helps new skin cells form, so wounds and irritation heal faster.
Dosage and Administration
Creams and ointments: apply a thin layer to the affected area once or several times a day, as directed on the label. Oral vitamin B complex products: take as directed on the label. Injections are given by a doctor or nurse, at the dose prescribed.
Interactions
- Injected Dexpanthenol should not be given within 12 hours of Neostigmine or other parasympathomimetic medicines, and should be used with care around Succinylcholine, as it may prolong its effect.
- Skin products have no important interactions.
Contraindications
- Allergy to Dexpanthenol or any ingredient.
- Injection: haemophilia (a bleeding disorder) and mechanical bowel obstruction.
Side Effects
Skin products rarely cause problems; some people get redness, itching or contact dermatitis. Injection may cause mild stomach cramps, diarrhoea or a brief fall in blood pressure.
Get urgent medical help if you develop swelling of the face or throat, difficulty breathing, a widespread rash, or severe abdominal pain after an injection.
Pregnancy and Lactation
Skin products and normal vitamin amounts are considered safe in pregnancy and breastfeeding. Cream used on cracked nipples should be wiped off before feeding if the label says so. Injections should only be used if your doctor advises.
Precautions and Warnings
Do not apply skin products to deep, infected or heavily bleeding wounds without medical advice. Stop using if irritation develops. Keep away from the eyes unless the product is made for eye use.
Overdose
Dexpanthenol has very low toxicity and overdose is unlikely. If a large amount is swallowed or too much is injected, contact a doctor for advice.
Therapeutic Class
Vitamin B5 derivative; skin protectant and wound-healing agent.
Storage
Store below 30°C in a dry place, away from light and out of the reach of children. Injections are stored as directed on the pack.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.