Indications
Pramoxine Hydrochloride (also called Pramocaine) is a local anaesthetic applied to the skin to relieve itching and pain. It is used for minor burns and sunburn, insect bites, minor cuts and scrapes, rashes such as from poison plants, eczema-related itching, and itching or discomfort from haemorrhoids (piles). It is found in creams, lotions, gels, sprays and rectal foams, sometimes combined with Hydrocortisone.
How It Works
Pramoxine blocks sodium channels in nerve endings in the skin. This stops nerves from sending itch and pain signals to the brain, numbing the area for a few hours. It does not treat the underlying cause of the itch or pain.
Dosage and Administration
For adults and children aged 2 years and over: apply a thin layer to the affected area up to 3 to 4 times daily, or as directed on the label. For haemorrhoids, apply to the anal area after cleaning and drying it, up to 5 times daily. Wash hands after use unless the hands are being treated. Do not use on large areas or under tight dressings unless advised. Do not use for more than 7 days without medical advice.
Interactions
No significant interactions are expected with medicines taken by mouth when used on small areas. Avoid applying other skin products to the same area at the same time unless your doctor advises.
Contraindications
Do not use if you are allergic to Pramoxine or any ingredient, on deep or puncture wounds, serious burns, or infected skin, or in the eyes or nose.
Side Effects
Side effects are uncommon and usually mild, such as stinging, burning, dryness or redness where it is applied. Rarely, an allergic skin reaction may occur.
Get urgent medical help if you develop a severe allergic reaction, such as swelling of the face, lips or throat, difficulty breathing or a widespread rash. Stop using it and see a doctor if the skin becomes more irritated, or if there is rectal bleeding.
Pregnancy and Lactation
Very little is absorbed through the skin, and short-term use on small areas is generally considered low risk. Ask your doctor or pharmacist before use in pregnancy or breastfeeding. Do not apply to the breast before feeding.
Precautions and Warnings
For external use only. Avoid contact with the eyes. See a doctor if symptoms worsen or last more than 7 days, or clear up and return within a few days. Not for children under 2 years unless a doctor advises. For haemorrhoid products, do not insert into the rectum with fingers or applicators unless the label says so.
Overdose
Overdose from skin use is unlikely. If a large amount is swallowed, especially by a child, seek medical advice or contact a poison centre.
Therapeutic Class
Topical local anaesthetic (antipruritic).
Storage
Store below 30°C in a dry place, away from light and out of the reach of children. Keep sprays away from heat and flame.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.