Affrox

Indications

Saffron is the dried red stigma (thread) of the Crocus sativus flower. In Unani and Ayurvedic medicine it is traditionally used as a general tonic, to lift low mood, to support digestion and appetite, for menstrual discomfort, and in preparations for sexual weakness. Some small studies suggest a mild benefit for low mood and premenstrual symptoms, but scientific evidence is limited and it should not replace prescribed treatment.

How It Works

Saffron contains natural compounds such as crocin, crocetin and safranal. These are antioxidants and are thought to influence brain chemicals involved in mood (such as serotonin). The exact way it works in traditional preparations is not fully known.

Dosage and Administration

Use as directed on the label or by a registered practitioner. Products usually contain small amounts of saffron, often with other herbs or honey. Do not take more than the recommended dose; very large amounts can be poisonous.

Interactions

Saffron may add to the effects of antidepressants (for example Fluoxetine, Sertraline), sedatives, blood pressure medicines and blood thinners such as Warfarin or Aspirin. Ask your doctor before using it with these medicines.

Contraindications

• Pregnancy (large amounts may stimulate the womb)
• Allergy to saffron or to plants such as Lolium, Olea (olive) or Salsola
• Bipolar disorder, unless advised by a doctor, as it may affect mood

Side Effects

At normal amounts it is usually well tolerated. Possible effects include dry mouth, nausea, headache, drowsiness, anxiety and change in appetite.

Get urgent medical help if large amounts are taken, or if there is yellowing of skin and eyes, unusual bleeding or bruising, vomiting, numbness, severe dizziness, or swelling of the face or difficulty breathing.

Pregnancy and Lactation

Do not use medicinal saffron preparations during pregnancy, because higher doses have been linked with miscarriage. Amounts used in cooking are generally considered safe. Safety during breastfeeding is not well known; avoid medicinal use.

Precautions and Warnings

Buy from reliable sources, as saffron is often adulterated. Tell your doctor before surgery, or if you have a bleeding disorder, low blood pressure or a mood disorder. Not recommended for children unless advised by a practitioner. Do not use it to replace treatment for depression or sexual problems without seeing a doctor.

Overdose

Taking 5 g or more can be toxic and may cause vomiting, bloody diarrhoea, bleeding, yellow skin, dizziness and numbness. Seek emergency medical help.

Therapeutic Class

Unani and Ayurvedic herbal preparation (tonic).

Storage

Store below 30°C in a dry place, away from light and out of the reach of children. Keep tightly closed.