Eprim 500 mg

Indications

Evening primrose oil is a food supplement made from the seeds of the evening primrose plant. It is traditionally used for breast pain linked to the menstrual cycle (cyclical mastalgia), premenstrual symptoms, menopausal hot flushes and dry, itchy skin such as eczema. Scientific evidence for these uses is limited and mixed, and it is not a substitute for medical treatment.

How It Works

The oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid. The body converts GLA into substances involved in controlling inflammation and keeping skin and cell membranes healthy. This is thought to explain its traditional uses, though how well it works is uncertain.

Dosage and Administration

Take as directed on the label or by a doctor. Capsules are usually taken by mouth with meals, once or a few times a day. Benefits, if any, may take 2 to 3 months to appear. Do not take more than the recommended amount.

Interactions

It may increase the risk of bleeding when taken with blood thinners such as Warfarin, Clopidogrel or Aspirin. It may lower the seizure threshold, so care is needed with Phenothiazines (such as Chlorpromazine) and in people taking medicines for epilepsy. Stop it at least 2 weeks before planned surgery and tell your doctor about it.

Contraindications

• Allergy to evening primrose or any ingredient.
• Bleeding disorders, unless a doctor advises otherwise.
• Use with caution, or avoid, in epilepsy or schizophrenia treated with Phenothiazines.

Side Effects

It is usually well tolerated. Possible effects include mild stomach upset, nausea, soft stools, headache and bloating. Taking it with food helps.

Get urgent medical help if you notice unusual bleeding or bruising, a seizure, or signs of a serious allergic reaction such as rash, swelling of the face or difficulty breathing.

Pregnancy and Lactation

Its safety in pregnancy is not well established, and it should not be used to start labour except under medical supervision. Avoid during pregnancy and breastfeeding unless a doctor advises it.

Precautions and Warnings

Tell your doctor if you have epilepsy, a bleeding problem or upcoming surgery, or take blood thinners. Do not use it in place of prescribed treatment for eczema, breast lumps or other conditions; any new breast lump should be checked by a doctor. Keep children away from capsules.

Overdose

Large amounts may cause stomach upset and diarrhoea. If a large quantity is swallowed, especially by a child, contact a doctor.

Therapeutic Class

Herbal food supplement (essential fatty acid, gamma-linolenic acid source).

Storage

Store below 30°C in a dry place, away from light and out of the reach of children.