Hexizen Hand Rub

Indications

Chlorhexidine gluconate is an antiseptic that kills a wide range of germs. It is used as a mouthwash or gel for gum inflammation (gingivitis), mouth ulcers, denture sores and oral hygiene after dental surgery or when brushing is difficult; as a skin cleanser or scrub for hand washing and before surgery or injections; for cleaning wounds and minor burns; and as a 7.1% gel applied to the newborn umbilical cord stump to prevent infection.

How It Works

Chlorhexidine damages the outer membrane of bacteria and some fungi, killing them. It sticks to the skin and the inside of the mouth, so it keeps working for several hours after use.

Dosage and Administration

• Mouthwash 0.2%: rinse 10 ml around the mouth for about 1 minute twice a day, then spit it out. Do not swallow.
• Mouthwash 0.12%: usually 15 ml twice a day, as directed on the pack.
• Skin cleanser or scrub: use as directed on the pack or by a health worker.
• Umbilical cord gel 7.1%: as advised by a doctor, nurse or health worker, usually applied to the cord stump once a day after birth.

Use the mouthwash at least 30 minutes after brushing with toothpaste, as toothpaste can weaken its effect. Do not eat or drink for a short time after rinsing.

Interactions

Toothpaste ingredients (sodium lauryl sulfate) can reduce the effect of the mouthwash. Tea, coffee and red wine make tooth staining more likely. Soap and some other skin products may inactivate it on the skin.

Contraindications

• Allergy to chlorhexidine or any ingredient of the product.
• Do not put into the ear if the eardrum may be damaged, and do not use on the brain, spinal cord or their coverings.

Side Effects

Mouthwash: brown staining of the teeth, tongue and fillings (can be removed by a dentist), changed taste, a burning feeling and more tartar. Skin: dryness, irritation or rash.

Chlorhexidine can rarely cause a severe allergic reaction. Get urgent medical help if you have swelling of the face, lips or throat, wheezing or difficulty breathing, a widespread rash, or feel faint after using it.

Pregnancy and Lactation

It can be used during pregnancy and breastfeeding, as very little is absorbed. If using it on the breasts, wash it off before feeding.

Precautions and Warnings

For external use and mouth rinsing only; do not swallow. Keep out of the eyes and ears; if it gets in the eyes, rinse well with water. Alcohol-based skin solutions are flammable: let them dry fully before any heat or electrical equipment is used. In premature babies, skin solutions can cause burns; use only as advised in hospital. Use the mouthwash for limited periods unless a dentist advises longer use.

Overdose

Swallowing a small amount of mouthwash is unlikely to cause serious harm, but may cause stomach upset. If a large amount is swallowed, especially by a child, or alcohol-based solution is swallowed, get medical help.

Therapeutic Class

Antiseptic and disinfectant (biguanide).

Storage

Store below 30°C, away from light and out of the reach of children. Keep alcohol-based solutions away from flames.