Lafrost

Indications

Docosanol cream is used to treat cold sores (fever blisters) on the lips and face caused by the herpes simplex virus. Started early, it can shorten healing time and ease symptoms such as tingling, itching, burning and pain.

How It Works

Docosanol is a long-chain fatty alcohol. It works on the surface of healthy skin cells and makes it harder for the cold sore virus to fuse with and enter them. This limits the spread of the virus to nearby cells, so the sore stays smaller and heals sooner. It does not kill the virus or remove it from the body.

Dosage and Administration

For adults and children aged 12 years and over: apply a thin layer to the cold sore or the tingling area 5 times a day, at the first sign of a cold sore, and continue until it has healed, usually for up to 10 days. Wash hands before and after use, rub in gently, and do not use more cream than needed. For children under 12, ask a doctor.

Interactions

No important interactions with medicines taken by mouth are known. Do not apply other creams, lip balms or cosmetics to the same spot at the same time unless advised.

Contraindications

Do not use if you are allergic to docosanol or any ingredient of the cream. Not for use inside the mouth, in or near the eyes, or on the genitals.

Side Effects

Side effects are uncommon and usually mild, such as headache, or skin irritation, dryness, redness or itching where the cream is applied.

Stop using and get urgent medical help for swelling of the face, lips or throat, difficulty breathing or a widespread rash. See a doctor if the sore spreads, is very painful, does not heal within 10 days, or if you have fever or sores near the eyes.

Pregnancy and Lactation

Very little docosanol is absorbed through the skin, and it is generally considered low risk, but there is limited data. Ask a doctor or pharmacist before use in pregnancy or while breastfeeding, and avoid applying it where the baby could touch it.

Precautions and Warnings

Cold sores are contagious: avoid kissing and sharing towels, cups or lip products while sores are present, and do not touch the sore except to apply cream. People with a weak immune system (for example on cancer treatment or with HIV) should see a doctor, as they may need stronger antiviral treatment.

Overdose

Using too much on the skin is unlikely to cause harm. If a large amount is swallowed, seek medical advice.

Therapeutic Class

Topical antiviral (cold sore treatment).

Storage

Store below 30°C, do not freeze. Keep the tube tightly closed, away from light and out of the reach of children.