Pyropin

Indications

Pyrantel Pamoate is a deworming medicine. It treats intestinal worm infections caused by roundworm, pinworm (threadworm) and hookworm, in adults and children.

How It Works

Pyrantel paralyses the worms by acting on their nerve and muscle system. The paralysed worms lose their grip on the gut wall and are passed out in the stool. Very little of the medicine is absorbed into the body.

Dosage and Administration

The dose is based on body weight: commonly 10 mg of pyrantel per kg as a single dose, up to a maximum of 1 g, or as directed on the label or by your doctor. For pinworm, the dose is usually repeated after 2 weeks. For hookworm, doses may be given for up to 3 days. Children's doses must be measured by weight as directed on the label or as prescribed. It can be taken at any time, with or without food; no fasting or laxative is needed. Shake the suspension well before use. Household members may need treating at the same time for pinworm.

Interactions

Do not use together with Piperazine, as they work against each other. It may raise Theophylline levels. Tell your doctor about other medicines you take.

Contraindications

• Allergy to pyrantel or any ingredient
• Use with care in liver disease
• Children under 1 year (or under 2 years for some products) unless advised by a doctor

Side Effects

Side effects are uncommon and usually mild: nausea, vomiting, loss of appetite, stomach cramps, diarrhoea, headache, dizziness, drowsiness and rash.

Get urgent medical help for swelling of the face or throat, trouble breathing, a severe rash, or yellow skin or eyes.

Pregnancy and Lactation

Avoid in the first 3 months of pregnancy unless a doctor advises. Very little is absorbed, but ask your doctor before using it in pregnancy or while breastfeeding.

Precautions and Warnings

To prevent reinfection, especially with pinworm: wash hands after using the toilet and before eating, keep nails short, change and wash underwear, nightwear and bed sheets, and avoid scratching around the bottom. See a doctor if symptoms continue.

Overdose

Overdose may cause stomach upset, dizziness and weakness. Seek medical advice.

Therapeutic Class

Anthelmintic (deworming medicine)

Storage

Store below 30°C in a dry place, away from light and out of the reach of children. Do not freeze the suspension.