Ticason

Indications

Fluticasone Propionate is a corticosteroid (steroid) used in several forms. Inhalers, often combined with Salmeterol, prevent asthma symptoms and are used for chronic obstructive pulmonary disease (COPD). Nasal sprays, sometimes combined with Azelastine, treat allergic rhinitis (sneezing, runny or blocked nose from allergies) and nasal polyps. Creams and ointments treat eczema and dermatitis.

How It Works

It reduces inflammation and swelling in the airways, the lining of the nose or the skin, which eases symptoms and, for asthma, makes attacks less likely over time.

Dosage and Administration

Nasal spray (50 mcg per spray), adults and children over 12: usually 2 sprays in each nostril once a day, reduced to 1 spray in each nostril once symptoms are controlled; full effect may take a few days. Inhalers: as prescribed, usually twice a day, every day even when you feel well; rinse your mouth with water and spit after each use. The inhaler does not relieve a sudden asthma attack, so always carry your reliever inhaler. Skin: apply a thin layer once or twice a day for the shortest time needed. Children: as prescribed.

Interactions

Ritonavir, Cobicistat, Ketoconazole, Itraconazole and Clarithromycin can greatly raise fluticasone levels and cause steroid side effects; tell your doctor if you take any of them. For combination inhalers containing Salmeterol, beta-blockers such as Propranolol can reduce the benefit and may worsen breathing.

Contraindications

Allergy to fluticasone or any ingredient (some inhalers contain lactose and milk protein). On the skin: untreated skin infections, acne, rosacea and the rash around the mouth called perioral dermatitis.

Side Effects

Nasal spray: nosebleeds, dryness or irritation in the nose, headache. Inhaler: hoarse voice, sore throat, oral thrush (white patches in the mouth) and cough. Skin: burning and, with long use, thinning. With long-term high doses: slower growth in children, cataracts or glaucoma, and reduced natural steroid production. Get urgent medical help if breathing gets worse right after using the inhaler, if an asthma attack is not relieved by your reliever, or for a serious allergic reaction or sudden vision changes.

Pregnancy and Lactation

Inhaled and nasal fluticasone are generally continued in pregnancy and breastfeeding when needed, because good asthma control is important for mother and baby. Use only as advised by a doctor. Do not apply skin products to the breasts before feeding.

Precautions and Warnings

Do not stop inhaled steroids suddenly without advice. Tell your doctor if you have tuberculosis or another untreated infection, eye problems such as glaucoma, or diabetes. Children on long-term treatment should have their height checked regularly. See a doctor if you need your reliever inhaler more often than usual.

Overdose

An occasional extra dose is unlikely to cause harm. Using higher doses than prescribed for a long time can suppress the body's own steroid production; seek medical advice.

Therapeutic Class

Corticosteroid (inhaled, intranasal and topical).

Storage

Store below 30°C in a dry place, away from light and out of the reach of children. Do not puncture, burn or overheat pressurised inhalers, even when empty.