Indications
Garcinia cambogia (also called Malabar tamarind, Garcinia gummi-gutta) is a tropical fruit whose rind is used as a food supplement, mainly in weight-management products. It is promoted to help control appetite and support weight loss. Studies show at best a small, short-term effect on weight, and it should only be used alongside a healthy diet and regular physical activity.
How It Works
The fruit rind contains hydroxycitric acid (HCA). In laboratory studies HCA blocks an enzyme the body uses to make fat and may affect appetite signals in the brain. These effects have not been shown convincingly in people.
Dosage and Administration
Take as directed on the label, usually before meals with a glass of water. Do not take more than the recommended amount and do not use it for more than 12 weeks without medical advice.
Interactions
Garcinia may lower blood sugar, so take care with diabetes medicines such as Insulin, Metformin or Glibenclamide. Cases of serotonin-related reactions have been reported when it was taken with antidepressants such as Sertraline, Fluoxetine or Escitalopram. Ask a doctor before combining it with statins such as Atorvastatin, with Warfarin, or with any medicine that can affect the liver.
Contraindications
- Liver disease, or a history of liver problems with supplements.
- Pregnancy and breastfeeding.
- People taking antidepressants that act on serotonin, unless a doctor agrees.
- Children and teenagers.
Side Effects
Possible effects include headache, nausea, stomach upset, diarrhoea and dizziness. Rare but serious cases of liver injury have been reported with weight-loss products containing Garcinia.
Get urgent medical help if you notice yellowing of the skin or eyes, dark urine, pale stools, severe tiredness, pain in the upper right abdomen, or symptoms such as agitation, fast heartbeat, high temperature, sweating and muscle twitching, or signs of a serious allergic reaction such as swelling of the face or difficulty breathing.
Pregnancy and Lactation
Do not use during pregnancy or breastfeeding. Safety has not been established and weight-loss products are not appropriate at these times.
Precautions and Warnings
Stop using it and see a doctor if you develop any signs of liver problems. People with diabetes should check blood sugar more often. Weight-loss supplements are not a substitute for medical treatment of obesity or related conditions such as diabetes and high blood pressure.
Overdose
Taking too much increases the risk of stomach upset and possibly liver injury. If a large amount is swallowed, especially by a child, get medical advice.
Therapeutic Class
Herbal food supplement used in weight-management products.
Storage
Store below 30°C in a dry place, away from light and out of the reach of children. Keep the container tightly closed.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.