Indications
Perilla (Perilla frutescens) is a leafy herb of the mint family widely used as food and in traditional East Asian medicine. Extracts of the leaf or seed are traditionally used for seasonal allergy symptoms such as sneezing, runny or blocked nose and itchy eyes, and for cough and minor stomach upset. In supplements it is often combined with other ingredients such as Quercetin and vitamin D. Some small studies suggest it may ease allergy symptoms, but scientific evidence is limited and it is not a cure.
How It Works
Perilla contains plant compounds such as rosmarinic acid and luteolin. In laboratory and small human studies these appear to reduce the release of histamine and other inflammatory signals from immune cells, which may lessen allergic reactions. Perilla seed oil is also rich in alpha linolenic acid, a plant omega 3 fatty acid.
Dosage and Administration
Take by mouth as directed on the label or by a registered practitioner. Do not exceed the stated amount. If allergy symptoms are severe, include wheeze or breathlessness, or do not improve, see a doctor rather than relying on a supplement.
Interactions
Few interactions are known. Because of limited data, take care if you use blood thinners such as Warfarin or antiplatelet medicines, or medicines that suppress the immune system, and tell your doctor about the supplement. It can be used alongside usual allergy medicines such as Cetirizine or nasal steroid sprays, but check with a pharmacist.
Contraindications
- Allergy to perilla or other plants of the mint family (such as basil, mint or sage), or to any other ingredient.
- Pregnancy, unless advised by a doctor.
Side Effects
Usually well tolerated at normal amounts. Possible: mild stomach upset, nausea and skin rash or contact skin irritation in sensitive people. Large amounts of raw perilla leaves have been linked to lung toxicity in animals, so concentrated or excessive use should be avoided.
Get urgent medical help for swelling of the face, lips or throat, wheezing, difficulty breathing or a widespread rash.
Pregnancy and Lactation
Safety in pregnancy and breastfeeding has not been established. Avoid perilla supplements during pregnancy and breastfeeding unless a doctor advises them; normal amounts used in food are not a concern.
Precautions and Warnings
Scientific evidence is limited, and supplements vary in content and quality. Not recommended for children unless a doctor advises. People with asthma should not stop their prescribed inhalers. Stop use if you notice any reaction.
Overdose
No specific overdose effects are well documented in people. Taking much more than directed may cause stomach upset; seek medical advice if a large amount is taken, especially by a child.
Therapeutic Class
Herbal preparation, traditional anti allergy supplement
Storage
Store below 30°C in a dry place, away from light and out of the reach of children.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.