Indications
Phosphorus is an essential mineral, taken as phosphate. As a medicine or supplement it is used:
- To prevent and treat low blood phosphate (hypophosphataemia), for example after poor nutrition, alcohol misuse, long-term antacid use, or some kidney and bone conditions
- As part of calcium, multivitamin and mineral products that support bone and teeth health
How It Works
Phosphate works with calcium to build and keep strong bones and teeth. It is also needed to make energy in every cell, for normal muscle and nerve function, and for the body’s acid balance.
Dosage and Administration
In combination supplements, take the amount on the product label. For treating low phosphate, the dose depends on blood tests and is as prescribed; levels of phosphate, calcium and kidney function are checked. Take with water, with or after food to reduce stomach upset. Do not take more than advised.
Interactions
- Antacids containing aluminium, magnesium or calcium, and Sevelamer, bind phosphate and reduce its absorption; take them at least 2 hours apart.
- Phosphate can reduce the absorption of Iron and Zinc supplements if taken together.
- Potassium phosphate products with potassium-sparing diuretics (Spironolactone, Amiloride) or ACE inhibitors (Enalapril, Ramipril) can raise blood potassium.
Contraindications
- High blood phosphate
- Severe kidney disease
- Phosphate kidney stones linked to infection
- Allergy to any ingredient of the product
Side Effects
Usually well tolerated at supplement doses. Higher doses can cause diarrhoea, nausea, stomach pain and bloating.
Get urgent medical help if there are muscle cramps or spasms, tingling around the mouth or in the fingers, an irregular heartbeat, confusion, or passing much less urine than usual, as these can be signs of too much phosphate or too little calcium.
Pregnancy and Lactation
Phosphorus is needed in normal amounts during pregnancy and breastfeeding, and usual supplement doses are considered safe. Higher treatment doses should be taken only as advised by the doctor.
Precautions and Warnings
- Tell the doctor about kidney disease, heart disease, or a low calcium level.
- People with kidney problems should take phosphate only under medical supervision.
- Long-term high doses need regular blood tests.
Overdose
Too much phosphate can lower blood calcium, causing cramps, tingling and spasms, and can harm the kidneys. Seek medical help, especially for children or people with kidney disease.
Therapeutic Class
Mineral supplement (electrolyte replacement).
Storage
Store below 30°C in a dry place, away from light and out of the reach of children.
Prepared by the Oshud Alo team from standard drug references. For information only; always follow your doctor's advice.